Take the F5 Freeway until the Mittagong exit (31). Continue along Old Hume Highway (31) until Centennial Road. Turn left onto Centennial Road until you see Centennial Vineyards on the left hand side.
From Canberra:
Take the F5 Freeway until the Berrima exit (31). Continue along Old Hume Highway (31) until Centennial Road. Turn right onto Centennial Road until you see Centennial Vineyards on the left hand side.